World Journal of Nuclear Medicine

CASE REPORT
Year
: 2021  |  Volume : 20  |  Issue : 4  |  Page : 401--404

Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma


Ram Elumalai Kumar1, Nitin Gupta1, Rajeev Ranjan2, Ritu Verma1, Ethel Shangne Belho1, Ishita Barat Sen3 
1 Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre, Sir Ganga Ram Hospital, New Delhi, India
2 Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India
3 Department of Nuclear Medicine and PET/CT, Fortis Memorial Research Institute, Gurugram, Haryana, India

Correspondence Address:
Dr. Nitin Gupta
Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre, Sir Ganga Ram Hospital, New Delhi - 110 060
India

18F-2-fluoro-2-deoxy-D-glucose ([18F]-FDG) positron emission tomography (PET) CT has proven useful in the evaluation of high-grade glioma and is also useful as a predictor of the degree of malignancy in newly diagnosed brain tumors. It is commonly accepted that high-grade gliomas are characterized by increased FDG uptake, whereas the low-grade glioma demonstrates reduced or absent FDG uptake. [18F]-FDOPA is an amino acid PET tracer which is a marker of the proliferative activity of brain tumors and demonstrates positive uptake in all grades of brain tumors; however, the degree of tracer uptake is significantly higher in high-grade tumors as compared to low-grade tumors. Here, we discuss a case where both FDG and DOPA PET/CT scans raised suspicion of low-grade glioma; however, the final histopathology report confirmed WHO grade IV Glioblastoma.


How to cite this article:
Kumar RE, Gupta N, Ranjan R, Verma R, Belho ES, Sen IB. Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma.World J Nucl Med 2021;20:401-404


How to cite this URL:
Kumar RE, Gupta N, Ranjan R, Verma R, Belho ES, Sen IB. Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma. World J Nucl Med [serial online] 2021 [cited 2022 Aug 11 ];20:401-404
Available from: http://www.wjnm.org/article.asp?issn=1450-1147;year=2021;volume=20;issue=4;spage=401;epage=404;aulast=Kumar;type=0