| CASE REPORT |
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| Year : 2021 | Volume
: 20
| Issue : 4 | Page : 389-391 |
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The role of nuclear medicine in a case of Rendu–Osler–Weber disease with pulmonary involvement
Carlyle Marques Barral1, Isabella Correa Chaves Nunes2, Shirleide Santos Nunes3, Sandra Monetti Dumont Sanches4
1 Densitometry and Nuclear Medicine Physician, Head of the Nuclear Medicine Service of Hospital das Clínicas-Federal University of Minas Gerais Clinics (HC-UFMG), Belo Horizonte, Minas Gerais, Brazill
2 Resident doctor, Head of the Nuclear Medicine Service of Hospital das Clínicas-Federal University of Minas Gerais Clinics (HC-UFMG), Belo Horizonte, Minas Gerais, Brazill
3 Radiopharmacist, Head of the Nuclear Medicine Service of Hospital das Clínicas-Federal University of Minas Gerais Clinics (HC-UFMG), Belo Horizonte, Minas Gerais, Brazill
4 Head of the Nuclear Medicine Service of Hospital das Clínicas-Federal University of Minas Gerais Clinics (HC-UFMG); Assistant Professor at the Department of Anatomy and Image, Faculty of Medicine, UFMG. Belo Horizonte, Minas Gerais, Brazill
Correspondence Address:
Dr. Carlyle Marques Barral
Rua Professor Morais, 476/901, Savassi, Belo Horizonte, Minas Gerais
Brazill
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DOI: 10.4103/wjnm.wjnm_48_21 
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Rendu–Osler–Weber syndrome or hereditary hemorrhagic telangiectasia (HHT) is a rare systemic disease. Its primary pathogenic expression is multiple arteriovenous malformations (AVM) and severe hypoxia. A case of suspected pulmonary embolism in a 49-year-old male with intestinal, cardiac, and pulmonary HHT affection is reported. Pulmonary AVM could create an apparent mismatch perfusion defect evident upon ventilation and perfusion scan (V/Q scan), leading to misinterpretation. It reinforces the importance between clinics, anatomy, and functional evaluation. Care must be taken when interpreting V/Q scan and the reporting physician must be alert to the possible sources of errors. |
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