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Year : 2018  |  Volume : 17  |  Issue : 4  |  Page : 213-218

Quantitative accuracy of positron emission tomography/magnetic resonance and positron emission tomography/computed tomography for cervical cancer

1 Department of Radiology, Division of Nuclear Medicine, University of North Carolina, Chapel Hill, NC, USA
2 Department of Radiology, Division of Abdominal Radiology, University of Texas-Southwestern, Dallas, Texas, USA
3 Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC, USA
4 Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC, USA
5 Department of Radiology, University of North Carolina, Chapel Hill, NC, USA
6 Department of Radiology, Stanford University, Palo Alto, CA, USA
7 Biomedical Research Imaging Center, Chapel Hill, NC, USA

Correspondence Address:
Jorge Daniel Oldan
Department of Radiology, University of North Carolina, Chapel Hill, NC 27514
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/wjnm.WJNM_56_17

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With the spread of positron emission tomography/magnetic resonance (PET/MR), the question of comparability of studies becomes important. We aim to determine whether PET/MR and PET/computed tomography (PET/CT) are comparable for the case of cervical cancer. Fifteen cervical cancer patients identified by either a radiation oncologist or an oncologic surgeon had both PET/MR and PET/CT performed for initial staging within 3 weeks. We then compared the results both quantitatively (measuring standardized uptake values [SUVs] on visible lesions) as well as qualitatively (having radiologists and nuclear medicine physicians interprets the results). While interpretations between PET/MR and PET/CT varied in many cases, SUVs of primary lesions were similar to within 25% in all but one case, and correlation coefficient was 0.92. Maximum SUV ranged between 4.9 and 25.2 for PET-MR and between 5.8 and 30.4 for PET-CT for primary tumors and between 1.5 and 18.8 for PET-MR and between 1.8 and 20.8 for PET-CT for nodes. However, clinical reads often varied significantly between PET/MR and PET/CT. This suggests that SUV is similar on PET/MR and PET/CT although the differing anatomic modalities available for correlation may make the difference in terms of qualitative interpretation.

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